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Post by nathalia on Aug 21, 2015 19:07:14 GMT -6
Hello! I made a word file (link below) with the information I found on double stranded RNA viruses. Let comments about what you thought. And I will be happy to answer your questions  dsRNA forum.docx (99.78 KB) |
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Post by dulanjani on Aug 22, 2015 1:02:13 GMT -6
I am interested about how these viral genomes get replicated in the host and i know it is important to know about viral replication as that is what they basically do inside a host cell. Did you find anything about how ds RNA viruses replicate? Do they replicate similar as retroviruses?any specific enzymes?
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bea
New Member
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Post by bea on Aug 22, 2015 11:52:34 GMT -6
Hello! I made a word file (link below) with the information I found on double stranded RNA viruses. Let comments about what you thought. And I will be happy to answer your questions Nath, really interesting what you posted about the HPV. I would like to know if we can find this virus out of USA? And what are the most commons symptoms that we can observe when the plant get infected, and if the vector can transmit more than one disease at the same time for the plant? |
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Post by gabriela on Aug 22, 2015 15:37:08 GMT -6
Thanks Nathy for the info.
I know that members of this group include the rotaviruses, that are the common cause of gastroenteritis in young children, and bluetongue virus, an economically important pathogen of cattle and sheep. Did you find something about the control or prevention of these type of virus?
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Post by nathalia on Aug 23, 2015 20:00:25 GMT -6
I am interested about how these viral genomes get replicated in the host and i know it is important to know about viral replication as that is what they basically do inside a host cell. Did you find anything about how ds RNA viruses replicate? Do they replicate similar as retroviruses?any specific enzymes? Answering your question on dsRNA virus replication: Reoviridae is the most studied family of the dsRNA virus group. Reoviruses have a double-stranded RNA along with a RNA-dependent RNA polymerase (RdRp) inside their capsid core. The entire infective-virus is taken up by the host cell, the outer envelope is digested revealing the capsid core. The capsid remains intact inside the cytoplasm. Inside the capsid, mRNA is synthesized from the negative strand of RNA, and these new mRNAs are released into the cytoplasm. These new mRNAs are either translated into proteins, or taken up by a new virus capsid. The new capsid takes up the mRNA, which is replicated to form a double-stranded RNA (virion). This is a youtube video I found that helped me understand better the replication process: www.youtube.com/watch?v=ok7ahEjs5cM |
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Post by nathalia on Aug 23, 2015 20:12:41 GMT -6
Hello! I made a word file (link below) with the information I found on double stranded RNA viruses. Let comments about what you thought. And I will be happy to answer your questions Nath, really interesting what you posted about the HPV. I would like to know if we can find this virus out of USA? And what are the most commons symptoms that we can observe when the plant get infected, and if the vector can transmit more than one disease at the same time for the plant? Answering your questions on HPV: I did a quick search in Plant Disease, and I have not found any reports of HPV outside the US. Yes, the vector can transmit more than one virus-disease to the host. In the case of wheat, HPV often occurs along with Wheat Streak Mosaic Virus (WSMV). Symptomatic wheat plants show strong mosaic, severe stunting and rapid decline leading to plant death. |
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Post by nathalia on Aug 23, 2015 20:38:23 GMT -6
Thanks Nathy for the info. I know that members of this group include the rotaviruses, that are the common cause of gastroenteritis in young children, and bluetongue virus, an economically important pathogen of cattle and sheep. Did you find something about the control or prevention of these type of virus? Answering your questions on rotavirus diseases: Children with gastroenteritis caused by rotaviruses show the following symptoms: severe diarrhea, vomiting, fever, pain and dehydration. The virus is shed into the feces, therefore touching contaminated objects and consuming contaminated food are the main means to spread the virus. One way to avoid the virus is to keep objects and surfaces clean, as well as consume safe food. The most important way to prevent rotavirus diseases is vaccines. There are vaccines available for young children (less than 1 year old), which are effective in preventing the rotavirus disease. Bluetongue virus disease in ruminants is transmitted by midges (small flies), and this virus is endemic to tropical and subtropical regions of the world. The disease can be more severe when weather conditions favor midge population reproduction. Bluetongue virus can be replicated in asymptomatic animals for long periods of time, which facilitates transmission to healthy animals. Sanitation is very important to avoid contact of midges with those animals. Vaccination is also an important control, however it has to be preventive because there is no curative treatment after the disease is confirmed. |
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Post by gabriela on Aug 23, 2015 21:05:01 GMT -6
Thanks nathy, I asked because I found that the frequency of gastroenteritis in the United is difficult to determine because of underreporting, especially of mild illness, which results in a variations resulting of estimated numbers of cases, hospitalizations, and deaths. I found that 179 million cases occur per year; being children more than 1.5 million. So the vaccine is available, but probably is a lit expensive... and that's why there are still high number of cases produced by these viruses. Thanks for the info Nathy..
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Post by jontrip247 on Aug 25, 2015 13:55:52 GMT -6
So if this virus acts the same in the plant system as it does the animal system, is it safe to say its shy?... Doesn't like to be naked.
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Post by gabriela on Aug 25, 2015 19:56:22 GMT -6
and they also do the same in fungi . Double-stranded (ds) RNAs have been observed in vegetative mycelium of the commercial basidiomycete Agrocybe aegerita, by gel-filtration chromatography. The presence of naked dsRNAs virus in this group of fungi was the first report of a naked and unencapsidated, viral genome fragments which suggested co-evolution with the host, or it also represented new replicating genetic elements (dsRNA “plasmids”) of unknown function, in a non pathogenic higher fungus. The name of the dsRNAs, was non mentioned, but it could be useful in some activities of the fungi? maybe it could be helping the fungi somehow in its immune system. I thought to share this info, since sometimes the entire infective-virus is taken up by the host cell, and the outer envelope is digested revealing the capsid core, so naked dsRNAs virus will be acting as a machinery for the host. |
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Post by Admin on Aug 27, 2015 12:47:02 GMT -6
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Post by gabriela on Aug 29, 2015 14:18:06 GMT -6
I was checking some information related to the rice dwarf virus suggested by Dr. Verchot. This virus is mostly distributed in Japan and Korea. A disease of rice in the Philippines formerly thought to be rice dwarf is now considered different. Host range is restricted to a few species of Gramineae. It is transmissible by the leafhoppers and not seed-transmitted in rice. RNA: About 11% of particle weight is double-stranded RNA, with a composition of 44% G + C. In diseased rice plants, chlorotic cells often contain a single intracellular body, usually near the cell nucleus. Is a devastated disease in rice.
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